DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma
نویسندگان
چکیده
منابع مشابه
Promoter methylation of DAL-1/4.1B predicts poor prognosis in non-small cell lung cancer.
PURPOSE DAL-1/4.1B is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. We have previously shown that a lung tumor suppressor, TSLC1, associates with DAL-1, suggesting that both proteins act in the same cascade. The purpose of this study is to understand the molecular mechanisms and clinical significance of DAL-1 inactivation...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2008
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6604452